al-Hakeem M S, McMillen M A
Department of Surgery, Bridgeport Hospital, Yale University, New Haven, Connecticut, USA.
Am J Surg. 1998 Sep;176(3):291-4. doi: 10.1016/s0002-9610(98)00155-x.
Abdominal pain is a common finding in patients with systemic lupus erythematosus (SLE), occurring in as many as half of all SLE patients in the course of their disease. The rheumatology and gastroenterology literature emphasizes etiologies of abdominal pain in patients with SLE such as peritonitis from polyserositis, dyspepsia from reflux, nausea and vomiting from bowel edema, ascites, mesenteric ischemia, pancreatitis, pneumatosis intestinalis from necrotizing enterocolitis, and hepatobiliary abnormalities. But in clinical practice, caring for SLE patients in a community teaching hospital, these seem to be rare entities.
A chart review study was performed of all patients with SLE with the diagnosis of abdominal pain admitted to a community teaching hospital between 1980 and 1995.
Of 13 patients who presented with abdominal pain, 9 required surgical intervention for cholecystitis, perforated ulcer, colonic perforation, diverticulitis, and adhesions. There were no negative laparotomies for polyserositis or bowel edema, or cases of mesenteric infarction or ascites.
Despite some unusual diagnostic possibilities in abdominal pain in SLE such as polyserositis and mesenteric infarction, and despite the superimposed problems of steroid therapy in most of the patients in this study, the majority of lupus patients with abdominal pain presenting at community hospitals have relatively conventional illnesses.
腹痛是系统性红斑狼疮(SLE)患者的常见症状,在所有SLE患者病程中,多达半数会出现腹痛。风湿病学和胃肠病学文献强调SLE患者腹痛的病因,如多浆膜炎引起的腹膜炎、反流引起的消化不良、肠水肿引起的恶心和呕吐、腹水、肠系膜缺血、胰腺炎、坏死性小肠结肠炎引起的肠壁囊样积气以及肝胆异常。但在临床实践中,在社区教学医院照料SLE患者时,这些情况似乎很少见。
对1980年至1995年间入住一家社区教学医院且诊断为腹痛的所有SLE患者进行了一项病历回顾研究。
在13例出现腹痛的患者中,9例因胆囊炎、溃疡穿孔、结肠穿孔、憩室炎和粘连而需要手术干预。没有因多浆膜炎或肠水肿而进行的阴性剖腹探查术,也没有肠系膜梗死或腹水的病例。
尽管SLE患者腹痛存在一些不寻常的诊断可能性,如多浆膜炎和肠系膜梗死,且尽管本研究中的大多数患者存在类固醇治疗带来的附加问题,但在社区医院就诊的大多数腹痛狼疮患者患有相对常见的疾病。