Young R A, Cegavske C F, Thompson R F
J Comp Physiol Psychol. 1976 May;90(5):424-34. doi: 10.1037/h0077219.
Excitability of the reflex nicitating membrane (NM) response to air puff and of the abducens motoneurons (final common path) to direct electrical stimulation (measured as amplitude of the evoked NM response) in rabbit was tested at various times after onset and offset of a 350-msec tone. Excitability to air puff showed a substantial increase during tone on a gradual decrease following tone off, in agreement with Ison and Leonard. Excitability of motoneurons showed a similar marked increase during tone on a transient decrease immediately following tone off, and then a gradual decrease. It is suggested that these excitability changes, which parallel closely the interstimulus-interval conditionability function reported by Gormezano for the same preparation, may provide an independent measure of the "molar stimulus trace". Excitability of abducens motoneurons tested in the intertrial intervals during subsequent tone-air puff conditioning showed no consistent changes. Surprisingly, animals given tone-abducens nucleus shock testing developed conditioned responses. In subsequent conditioning, using standard tone-air puff training, they showed 85% savings in acquisition relative to nonstimulated controls.
在350毫秒音调开始和结束后的不同时间，测试了兔的反射性瞬膜（NM）对吹气的兴奋性以及外展运动神经元（最终共同通路）对直接电刺激的兴奋性（以诱发的NM反应幅度衡量）。对吹气的兴奋性在音调持续期间显著增加，在音调结束后逐渐降低，这与伊森和伦纳德的研究结果一致。运动神经元的兴奋性在音调持续期间有类似的显著增加，在音调结束后立即短暂降低，然后逐渐降低。有人认为，这些兴奋性变化与戈尔梅扎诺报道的同一实验准备中刺激间隔条件化函数密切平行，可能提供了一种对“整体刺激痕迹”的独立测量方法。在随后的音调-吹气条件化的试验间隔中测试的外展运动神经元的兴奋性没有一致的变化。令人惊讶的是，接受音调-外展神经核电击测试的动物产生了条件反应。在随后使用标准音调-吹气训练的条件化中，相对于未受刺激的对照组，它们在习得方面节省了85%。
