Zinn K
Division of Biology, California Institute of Technology, Pasadena, California 91125, USA.
Curr Biol. 1998 Oct 8;8(20):R725-6. doi: 10.1016/s0960-9822(98)70459-2.
Recent work on the Caenorhabditis elegans clr-1 gene shows that the receptor tyrosine phosphatase that it encodes negatively regulates a receptor tyrosine kinase related to mammalian fibroblast growth factor receptors. This opens up a promising system for investigating receptor tyrosine phosphatase function.
近期对秀丽隐杆线虫clr-1基因的研究表明,它所编码的受体酪氨酸磷酸酶对一种与哺乳动物成纤维细胞生长因子受体相关的受体酪氨酸激酶起负向调节作用。这为研究受体酪氨酸磷酸酶的功能开辟了一个有前景的系统。