Grunze H, Dittert S, Bungert M, Erfurth A
Psychiatrische Klinik der Universität,München, Deutschland.
Neuropsychobiology. 1998 Oct;38(3):198-9. doi: 10.1159/000026537.
A bipolar I manic patient was treated successfully by adding gabapentin to perazine and clonazepam. Also initially tolerated well, an increase of creatinine after several weeks of GP (2000 mg) was observed which was reversible after discontinuation of GP. It is suggested that the possibility of renal dysfunction should be kept in mind with the usage of gabapentin.
一名双相I型躁狂症患者通过在奋乃静和氯硝西泮的基础上加用加巴喷丁得到成功治疗。起初耐受性也良好，但在服用加巴喷丁（2000毫克）几周后观察到肌酐升高，停用加巴喷丁后肌酐升高情况可逆转。提示使用加巴喷丁时应留意肾功能障碍的可能性。
