Farup P G, Modalsli B, Tholfsen J
Department of Medicine, Gjøvik County Hospital, Norway.
Dis Esophagus. 1998 Apr;11(2):116-9. doi: 10.1093/dote/11.2.116.
The study analyzes the natural esophageal restricturing process after dilatation of peptic esophageal strictures. Fifty patients (male/female: 30/20) with median age 71 years (range 20-87) with peptic esophageal strictures were dilated with hydrostatic balloons to 20 mm and followed up for 12 months. Stricture size was measured with a 'balloon pull-through' technique before the dilatations, and at follow-ups after 6 and 12 months. The restricturing rate was defined as the difference in stricture diameter at two measurements divided by the time interval. The mean restricturing rate during the first and last 6 month periods were 0.99 and 0.02 mm/month respectively (P < 0.001), and during the first 6 months the restricturing rates were 1.98 and 0.69 mm/month in patients redilated and not redilated respectively (P < 0.001). A tight stricture at the initial dilatation, a long history of reflux symptoms and a short history of dysphagia were all significantly related to a high restricturing during the first 6 months (P < 0.001).
该研究分析了消化性食管狭窄扩张术后食管的自然再狭窄过程。50例消化性食管狭窄患者（男/女：30/20），中位年龄71岁（范围20 - 87岁），采用水压球囊扩张至20毫米，并随访12个月。在扩张前以及6个月和12个月随访时，采用“球囊通过”技术测量狭窄尺寸。再狭窄率定义为两次测量的狭窄直径之差除以时间间隔。前6个月和后6个月期间的平均再狭窄率分别为0.99和0.02毫米/月（P < 0.001），在前6个月中，再次扩张和未再次扩张的患者再狭窄率分别为1.98和0.69毫米/月（P < 0.001）。初始扩张时的紧密狭窄、反流症状的长期病史以及吞咽困难的短期病史均与前6个月的高再狭窄显著相关（P < 0.001）。
