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早期乳腺癌诊断与治疗后的精神疾病发病率

Psychiatric morbidity following the diagnosis and treatment of early breast cancer.

作者信息

Farragher B

机构信息

University College Hospital, Galway.

出版信息

Ir J Med Sci. 1998 Jul-Sep;167(3):166-9. doi: 10.1007/BF02937931.

Abstract

Psychiatric illness associated with breast cancer still goes unrecognised and untreated. A prospective study was carried out on a consecutive series of 33 patients with early breast cancer. Patients were interviewed following their diagnosis and 3 to 6 months post-mastectomy. Patients also completed the General Health Questionnaire 60 (GHQ 60) and the Leeds Scales for the Self-Assessment of Anxiety and Depression. Seven patients suffered from a depressive disorder at the post-operative interview. One patient suffered from an anxiety disorder. One of the depressed patients had received antidepressant medication from her general practitioner. The GHQ 60 was able to predict depressive illness in the post-operative period with a sensitivity of 71 per cent at the pre-operative diagnostic stage. This study is consistent in its findings of increased psychiatric morbidity in early breast cancer patients in the months after surgery. It also highlights the usefulness of a self assessment questionnaire in predicting it.

摘要

与乳腺癌相关的精神疾病仍未得到识别和治疗。对连续的33例早期乳腺癌患者进行了一项前瞻性研究。患者在确诊后及乳房切除术后3至6个月接受访谈。患者还完成了一般健康问卷60(GHQ 60)以及利兹焦虑和抑郁自评量表。7例患者在术后访谈时患有抑郁症。1例患者患有焦虑症。其中1例抑郁症患者曾从她的全科医生那里接受过抗抑郁药物治疗。GHQ 60能够在术前诊断阶段以71%的敏感度预测术后抑郁疾病。这项研究在其关于早期乳腺癌患者术后数月精神疾病发病率增加的研究结果上是一致的。它还突出了一份自评问卷在预测方面的有用性。

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