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HLA DQA1 genotyping of Chinese in Taiwan by PCR-RFLP.

作者信息

Lo F S, Chang J G, Lee Y J, Linacre A, Lee J C

机构信息

Departement of Pediatrics, Mackay Memmorial Hospital, Taipei, Republic of China.

出版信息

Kaohsiung J Med Sci. 1998 Aug;14(8):458-63.

PMID:9780594
Abstract

Population data were established for the HLA DQA1 locus among 147 Chinese in Taiwan by the PCR-RFLP flowchart system. Twelve alleles could be differentiated in this study, although only nine alleles were found among the above samples. There were no discrepancies in the results obtained by PCR-RFLP when compared to the results obtained by the AmpliType HLA DQ alpha typing kit. Using the Chi-square test, significant differences were observed (p < 0.005) between this data and that for Japanese, African Americans and US Caucasians. The observed heterozygosity was 83% with a discrimination power of 0.93.

摘要

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