Konno H
2nd Department of Surgery, Hamamatsu University School of Medicine.
Nihon Rinsho. 1998 Sep;56(9):2401-4.
Ulcer bleeding in the upper gastrointestinal tract is one of severe complications in the patients with abdominal aortic aneurysm (AAA). Retrospective analysis of patients with AAA and prospective endoscopic study revealed ulcer lesions occurred more frequently in AAA patients than in controls. Decreased gastric mucosal blood flow (GMBF) and accompanied consumption coagulopathy (CC) mainly contribute to the development of postoperative ulcer bleeding. Recently, the number of AAA patients with ulcer bleeding has been decreased remarkably after we started the anti-ulcer therapy for AAA patients with low GMBF or/and the administration of heparin for the patients with CC.
上消化道溃疡出血是腹主动脉瘤（AAA）患者的严重并发症之一。对AAA患者的回顾性分析和前瞻性内镜研究表明，AAA患者溃疡病变的发生率高于对照组。胃黏膜血流量（GMBF）减少以及伴随的消耗性凝血病（CC）是术后溃疡出血发生的主要原因。最近，在我们开始对GMBF较低的AAA患者进行抗溃疡治疗和/或对CC患者使用肝素后，AAA合并溃疡出血的患者数量显著减少。
