McIntosh S A, Purushotham A D
University Department of Surgery, Western Infirmary, Glasgow, UK.
Br J Surg. 1998 Oct;85(10):1347-56. doi: 10.1046/j.1365-2168.1998.00934.x.
Sentinel lymph node biopsy is a recently developed, minimally invasive technique for staging the axilla in patients with breast cancer. It has been suggested that this technique will avoid the morbidity associated with more extensive axillary dissection. A wide range of different methods and materials has been employed for lymphatic mapping, but there has been little consensus on the most reliable and reproducible technique.
This is a comprehensive review of all published literature on sentinel node biopsy in breast cancer, using the Medline and Embase databases and cross-referencing of major articles on the subject.
Sentinel node biopsy is a valid technique in breast cancer management, providing valuable axillary staging information. The optimal technique of lymphatic mapping utilizes a combination of vital blue dye and radiolabelled colloid. However, there remain controversial issues which require to be resolved before sentinel node biopsy becomes a widely accepted part of breast cancer care.
前哨淋巴结活检是一种最近开发的用于乳腺癌患者腋窝分期的微创技术。有人认为该技术将避免与更广泛腋窝清扫相关的发病率。已经采用了多种不同的方法和材料进行淋巴绘图，但对于最可靠和可重复的技术几乎没有共识。
这是对所有已发表的关于乳腺癌前哨淋巴结活检的文献的全面综述，使用Medline和Embase数据库并对该主题的主要文章进行交叉引用。
前哨淋巴结活检是乳腺癌治疗中的一种有效技术，可提供有价值的腋窝分期信息。淋巴绘图的最佳技术是使用活性蓝色染料和放射性标记胶体的组合。然而，在进行前哨淋巴结活检成为乳腺癌治疗广泛接受的一部分之前，仍有一些有争议的问题需要解决。
