逆转录病毒颗粒组装中的分子事件。
Molecular events in the assembly of retrovirus particles.
作者信息
Sakalian M, Hunter E
机构信息
Department of Microbiology, University of Alabama at Birmingham, USA.
出版信息
Adv Exp Med Biol. 1998;440:329-39. doi: 10.1007/978-1-4615-5331-1_43.
PMID:9782300
Abstract
Retrovirus assembly results from the ability of a single gene product, the gag polyprotein precursor, to coalesce into a spherical particle capable of release from the cell. In conjunction with this primary process of capsid formation additional viral gene products such as the replicative enzymes and envelope glycoproteins as well as the genomic RNA are incorporated to form an infectious virus.
摘要
逆转录病毒的组装源于单一基因产物——gag多蛋白前体聚集成能够从细胞中释放的球形颗粒的能力。在衣壳形成的这一主要过程中，其他病毒基因产物，如复制酶、包膜糖蛋白以及基因组RNA也被整合进来，以形成具有感染性的病毒。
Zotero 插件