日本东北地区猪群中人类冠状病毒的血清学调查。
A serological survey of human coronavirus in pigs of the Tohoku District of Japan.
作者信息
Hirano N, Ono K
机构信息
Department of Veterinary Microbiology, Iwate University, Morioka, Japan.
出版信息
Adv Exp Med Biol. 1998;440:491-4. doi: 10.1007/978-1-4615-5331-1_63.
A total of 2496 swine sera from 60 farms in the Tohoku District of Japan was examined for hemagglutination inhibiting (HI) antibodies to human coronavirus (HCV), swine hemagglutinating encephalomyelitis virus (HEV) and bovine coronavirus (BCV). HI antibodies to HCV OC43 strain and HEV 67N strain were highly prevalent with positivity rates of 91.4 and 82.1%, respectively, while the BCV Kakegawa strain was 44.2% positive. Farm D in Miyagi Prefecture showed the highest antibody titers to HCV OC43 strain with geometric mean titers (GMT) of 1:200. These results suggest that pigs might be infected with HCV or an antigenetically related virus as well as HEV.
对来自日本东北地区60个农场的2496份猪血清进行了检测，以检测其针对人类冠状病毒（HCV）、猪血凝性脑脊髓炎病毒（HEV）和牛冠状病毒（BCV）的血凝抑制（HI）抗体。针对HCV OC43株和HEV 67N株的HI抗体高度流行，阳性率分别为91.4%和82.1%，而BCV挂川株的阳性率为44.2%。宫城县的农场D对HCV OC43株的抗体滴度最高，几何平均滴度（GMT）为1:200。这些结果表明，猪可能感染了HCV或抗原相关病毒以及HEV。
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