The role of subunit interfaces for the nicotinic acetylcholine receptor's allosterism.
作者信息
Hucho F, Methfessel C, Watty A
机构信息
Freie Universität Berlin, Institut für Biochemie, Germany.
出版信息
J Physiol Paris. 1998 Apr;92(2):85-8. doi: 10.1016/S0928-4257(98)80143-5.
PMID:9782449
Abstract
Cross-linking of nicotinic acetylcholine receptors, combined with binding studies and patch-clamp electrophysiology, has proven the existence of a 'pre-existing equilibrium' of functional states and the functional role of subunit interfaces, two key postulates of the allosteric model.
摘要
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