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康复期间使用氟西汀治疗情感障碍。

Treatment of emotionalism with fluoxetine during rehabilitation.

作者信息

Tsai W C, Lai J S, Wang T G

机构信息

Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, R.O.C.

出版信息

Scand J Rehabil Med. 1998 Sep;30(3):145-9. doi: 10.1080/003655098444075.

DOI:10.1080/003655098444075
PMID:9782541
Abstract

Emotionalism (emotional lability) is a common but distressing phenomenon that occurs frequently in individuals suffering cerebral vascular accidents and other brain diseases. Patients with emotionalism sometimes embarrass their families and themselves, becoming socially disabled despite normal physical function. At its worst, emotionalism interferes with rehabilitation programs, delays progress and sometimes makes these programs impossible. This paper reports the effect of fluoxetine in treating three patients with persistent emotionalism (2 cases following cerebrovascular accidents, 1 case following encephalitis). All 3 patients demonstrated dramatic improvement in emotionalism within 6 days of treatment. The severity, frequency and duration of each episode were reduced greatly. The treatment improved the effectiveness of the rehabilitation program, relieved patient and family embarrassment, and enabled patients to resume rapidly their previous lifestyle patterns. All patients reached the functional goals planned prior to the onset of rehabilitation. We conclude that fluoxetine is highly effective in treating the symptoms of emotionalism in all patients, and allows for recovery of both physical and social function.

摘要

情感易激惹(情绪不稳定)是一种常见但令人苦恼的现象,常见于脑血管意外及其他脑部疾病患者。情感易激惹患者有时会令家人和自己尴尬,尽管身体功能正常,但却导致社交障碍。在最糟糕的情况下,情感易激惹会干扰康复计划,延缓康复进程,有时甚至使这些计划无法实施。本文报道了氟西汀治疗3例持续性情感易激惹患者(2例脑血管意外后,1例脑炎后)的疗效。所有3例患者在治疗6天内情感易激惹症状均有显著改善。每次发作的严重程度、频率和持续时间均大幅降低。治疗提高了康复计划的效果,减轻了患者及其家人的尴尬,并使患者能够迅速恢复以前的生活方式。所有患者均达到康复开始前计划的功能目标。我们得出结论,氟西汀在治疗所有患者的情感易激惹症状方面非常有效,并能使身体和社会功能恢复。

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Treatment of emotionalism with fluoxetine during rehabilitation.康复期间使用氟西汀治疗情感障碍。
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Degener Neurol Neuromuscul Dis. 2013 May 27;3:23-31. doi: 10.2147/DNND.S34160. eCollection 2013.
2
Current concepts in the pharmacotherapy of pseudobulbar affect.假性延髓情绪障碍的药物治疗的当前概念。
Drugs. 2011 Jun 18;71(9):1193-207. doi: 10.2165/11591450-000000000-00000.
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Pathological laughing and crying : epidemiology, pathophysiology and treatment.病理性哭笑:流行病学、病理生理学与治疗
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