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[克瓦马特和奥美唑对实验性十二指肠溃疡消化系统不同部位谷胱甘肽系统作用的比较评估]

[A comparative evaluation of the action of kvamatel and omez on the glutathione system in different sections of the digestive system in experimental duodenal ulcer].

作者信息

Daminov Sh N, Inoiatova F Kh

机构信息

Central Research Laboratory, Second Tashkent Medical Institute, Uzbekistan.

出版信息

Eksp Klin Farmakol. 1998 Jul-Aug;61(4):26-8.

PMID:9783104
Abstract

Experiments on male albino rats demonstrated significant changes in the content of oxidized and reduced glutathione in the tissues of the liver, pancreas, stomach, duodenum, and small intestine in acetate ulcer of the duodenum. Experimental therapy with quamatel and particularly with omez led to activation of the glutathione system in the tissues under and in this way increased their resistance to the ulcerogenic effect.

摘要

对雄性白化病大鼠进行的实验表明,十二指肠醋酸溃疡时,肝脏、胰腺、胃、十二指肠和小肠组织中氧化型和还原型谷胱甘肽的含量发生了显著变化。用夸马特和特别是奥美进行实验性治疗可激活这些组织中的谷胱甘肽系统,从而提高它们对致溃疡作用的抵抗力。

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1
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