Farine D, Granovsky-Grisaru S, Ryan G, Seaward P G, Teoh T G, Laskin C, Ritchie J W
Perinatal Unit, Mount Sinai Hospital, Toronto, Ontario, Canada.
J Clin Ultrasound. 1998 Oct;26(8):379-82. doi: 10.1002/(sici)1097-0096(199810)26:8<379::aid-jcu1>3.0.co;2-f.
We evaluated the role of umbilical artery Doppler velocimetry in the surveillance of pregnancies complicated by systemic lupus erythematosus (SLE).
We retrospectively studied 56 women with SLE whose pregnancies were managed at our perinatal center between 1988 and 1995.
Absent or reversed end-diastolic flow velocity was detected in 6 (11%) of 56 patients. This sub-group of patients had an increased risk of pre-eclampsia, intrauterine growth restriction, cesarean section, and preterm delivery.
A high incidence (11%) of abnormal umbilical artery waveforms was detected. This finding was associated with an increased risk of maternal and fetal complications.
我们评估了脐动脉多普勒血流测定在监测合并系统性红斑狼疮（SLE）妊娠中的作用。
我们回顾性研究了1988年至1995年间在我们围产期中心管理妊娠的56例SLE女性患者。
56例患者中有6例（11%）检测到舒张末期血流速度缺失或反向。该亚组患者发生先兆子痫、宫内生长受限、剖宫产和早产的风险增加。
检测到脐动脉波形异常的发生率较高（11%）。这一发现与母婴并发症风险增加有关。
