Hany M A, Bouvier R, Ranchère D, Bergeron C, Schell M, Chappuis J P, Philip T, Frappaz D
Service de Pédiatrie, Centre Léon Bérard, Lyon, France.
Pediatr Hematol Oncol. 1998 Sep-Oct;15(5):437-41. doi: 10.3109/08880019809016573.
The sacrococcygeal region may be the origin of germinal tumors, of paragangliomas, and, rarely, of extradural myxopapillary ependymomas (MPE) in the newborn and child. A case is presented of a preterm child with an abdominal tumor, originating from the precoccygeal area, that turned out to be a teratoma with a component of an MPE. The high levels of alpha-fetoprotein in this preterm baby were initially misleadingly interpreted as a tumoral marker. The differential diagnosis and the difficulties in interpreting tumoral markers in infants are discussed.
骶尾区域可能是新生儿和儿童生殖细胞瘤、副神经节瘤的起源部位,硬膜外黏液乳头型室管膜瘤(MPE)的起源则较为罕见。本文报告了1例早产患儿,其腹部肿瘤起源于尾骨前区域,病理结果显示为含有MPE成分的畸胎瘤。该早产婴儿甲胎蛋白水平升高,最初被误导性地解读为肿瘤标志物。本文讨论了婴儿肿瘤标志物的鉴别诊断及解读难点。