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[抗Re-糖脂抗体缺乏的新生儿肠道菌群失调的发展]

[The development of intestinal dysbacteriosis in newborn infants with a deficiency of antibodies to the Re-glycolipid].

作者信息

Likhoded V G, Chkhaidze I G, Galdavadze M A, Likhoded N V, Lobova E A, Iakovlev M Iu

机构信息

Research and Production Centre Hydrobios, Institute of Human Morphology, Moscow, Russia.

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1998 Jul-Aug(4):67-8.

PMID:9783406
Abstract

The dependence of the quantitative content of Escherichia coli in the feces of newborn infants 3 days after birth on the titer of anti Re-glycolipid antibodies in umbilical blood and in mother milk was studied. The reverse correlation between the number of bacteria in feces and the titers of anti Re-glycolipid antibodies was established, the amount of bacteria depending more on antibody titers in umbilical blood than on those in mother milk. The conclusion was made that antiglycolipid antibodies played an important role in the regulation of the quantitative content of E. coli in the intestine of newborn infants. In case of the deficiency of such antibodies intestinal dysbacteriosis may develop in newborn infants.

摘要

研究了出生3天的新生儿粪便中大肠杆菌的定量含量与脐血和母乳中抗Re-糖脂抗体滴度之间的关系。确定了粪便中细菌数量与抗Re-糖脂抗体滴度之间呈负相关,细菌数量更多地取决于脐血中的抗体滴度而非母乳中的抗体滴度。得出结论,抗糖脂抗体在新生儿肠道中大肠杆菌定量含量的调节中起重要作用。若缺乏此类抗体,新生儿可能会发生肠道菌群失调。

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