细胞黏附分子样蛋白酪氨酸磷酸酶LAR、RPTPδ和RPTPσ在小鼠中的发育表达
Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.
作者信息
Schaapveld R Q, Schepens J T, Bächner D, Attema J, Wieringa B, Jap P H, Hendriks W J
机构信息
Department of Cell Biology and Histology, Institute of Cellular Signalling, University of Nijmegen, Adelbertusplein 1, 6525 EK, Nijmegen, The Netherlands.
出版信息
Mech Dev. 1998 Sep;77(1):59-62. doi: 10.1016/s0925-4773(98)00119-1.
Using RNA in situ hybridization we compared the expression patterns of the cell adhesion molecule-like receptor-type protein tyrosine phosphatases LAR, RPTP sigma and RPTP sigma during mouse development. We found that LAR is expressed in basal lamina-associated epithelial tissues of (neuro)ectodermal, neural crest/ectomesenchyme and endodermal origin. RPTP sigma is found in (neuro)ectodermal, neural crest-derived systems and in mesoderm-derived tissues. The expression pattern of RPTP sigma largely parallels that of RPTP sigma, in concordance with their proposed evolutionary history
我们使用RNA原位杂交技术比较了细胞黏附分子样受体型蛋白酪氨酸磷酸酶LAR、RPTPσ和RPTPσ在小鼠发育过程中的表达模式。我们发现LAR在（神经）外胚层、神经嵴/外胚间充质和内胚层来源的基膜相关上皮组织中表达。RPTPσ存在于（神经）外胚层、神经嵴衍生系统和中胚层衍生组织中。RPTPσ的表达模式与RPTPσ基本平行，这与其推测的进化史一致。
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