高浓度会导致血小板激活吗？一项关于高浓度随机供体血小板的流式细胞术研究。
Does hyperconcentration result in platelet activation?. A flow-cytometric study of hyperconcentrated random donor platelets.
作者信息
Gollehon T J, King D E, Craig F E
机构信息
The University of Texas Health Science Center, San Antonio, Tex., USA.
出版信息
Vox Sang. 1998;75(2):124-7.
BACKGROUND AND OBJECTIVES
Hyperconcentration of platelets may lead to platelet activation and loss of platelet function.
MATERIALS AND METHODS
Platelet activation following hyperconcentration was assessed using flow-cytometric detection of platelet P-selectin expression and platelet swirling.
RESULTS
Platelet hyperconcentration led to a minimal increase in P-selectin expression and no difference in platelet swirling.
CONCLUSION
Hyperconcentration was not associated with a clinically significant change in platelet activation and had no significant effect on platelet quality as detected by pH and platelet yield.
背景与目的
血小板过度浓缩可能导致血小板活化及血小板功能丧失。
材料与方法
使用流式细胞术检测血小板P-选择素表达及血小板聚集来评估过度浓缩后的血小板活化情况。
结果
血小板过度浓缩导致P-选择素表达略有增加，血小板聚集无差异。
结论
过度浓缩与血小板活化的临床显著变化无关，对通过pH值和血小板产量检测的血小板质量无显著影响。
Zotero 插件