Butov Iu L, Sadchikov V D, Khusnutdinov Sh M, Kharchenko A V
Lik Sprava. 1998 Jun(4):69-71.
The neoplasms and gastric mucosa colonization with Helicobacter pylori was studied in 40 stomachs resected for expansive (n = 20) and infiltrative (n = 20) carcinoma using Giemsa staining histological sections, histochemical reactions to oxyreductase, and urease test. In expansive carcinoma of the stomach, H. pylori was identifiable both in the tumour and surrounding gastric mucosa in 70 per cent of cases; infiltrative carcinoma appeared to be associated with gastric mucosa H. pylori in 80 per cent, whereas tumour H. pylori were recordable in 30 per cent of cases, which fact is dependent upon the histological structure of carcinoma. The role H. pylori plays in cancerogenesis is discussed.
利用吉姆萨染色组织切片、氧化还原酶组织化学反应及尿素酶试验，对40例因胃扩张性癌（n = 20）和浸润性癌（n = 20）而切除的胃进行了肿瘤及幽门螺杆菌胃黏膜定植情况的研究。在胃扩张性癌中，70%的病例在肿瘤及周围胃黏膜中均可识别出幽门螺杆菌；浸润性癌似乎在80%的病例中与胃黏膜幽门螺杆菌有关，而在30%的病例中可记录到肿瘤内的幽门螺杆菌，这一情况取决于癌的组织结构。文中讨论了幽门螺杆菌在致癌过程中所起的作用。
