[海马体长期增强效应晚期与双脉冲易化相互作用的细胞内研究]
[Intracellular study of interaction of paired-pulse facilitation and late phase of hippocampal long-term potentiation].
作者信息
Voronin L L, Rossokhin A V, Sokolov M V
机构信息
Brain Research Institute of the Russian Acad. Med. Sci., Moscow, Russia.
出版信息
Ross Fiziol Zh Im I M Sechenova. 1998 May-Jun;84(5-6):426-35.
PMID:9785407
Abstract
Presynaptic paired-pulse facilitation (PPF) rate decreased in most CA1 pyramidal neurones following the long-term potantiation (LTP) induction. The decrease correlated with the LTP magnitude as well as with the initial (pretetanic) PPF rate. The data obtained suggests an involvement of presynaptic mechanisms in maintaining the early and the delayed LTPs.
摘要
在长期增强（LTP）诱导后，大多数CA1锥体神经元的突触前配对脉冲易化（PPF）率降低。这种降低与LTP幅度以及初始（强直前）PPF率相关。所获得的数据表明突触前机制参与维持早期和延迟LTP。
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