Shapiro F B, Umarova B A, Strukova S M
Moscow State University, Vorobyevy Gory, Russia.
Ross Fiziol Zh Im I M Sechenova. 1998 May-Jun;84(5-6):469-73.
Administration of non-selective beta-blocker propranolol prevented the stress-activated action whereas the alpha-agonist isoprenaline enhanced the effect of immobilisation stress on the rat mast cells. beta-antagonists or agonists exerted no effect on the heparine secretion by the mast cells. ACTH activated the secretion in the absence of stress.
给予非选择性β受体阻滞剂普萘洛尔可阻止应激激活作用,而α受体激动剂异丙肾上腺素则增强了束缚应激对大鼠肥大细胞的作用。β受体拮抗剂或激动剂对肥大细胞的肝素分泌无影响。促肾上腺皮质激素在无应激情况下激活分泌。