Marklund M, Franklin K A, Stenlund H, Persson M
Department of Orthodontics, Umeå University, Sweden.
Eur J Oral Sci. 1998 Oct;106(5):914-21. doi: 10.1046/j.0909-8836.1998.eos106503.x.
The aim of the present study was to evaluate whether the outcome of treatment using an intraoral mandibular advancement device in patients with obstructive sleep apnoea is associated with the mandibular morphology. The effects of the device on apnoeas and sleep were evaluated in 32 men with obstructive sleep apnoea in continuous polysomnographic sleep recordings including body position, during one night without the device and one night with it. Mandibular morphology variables were measured on cephalograms. The odds ratio for a supine apnoea-hypopnoea index of below 15 during treatment was 17 for a mandibular plane angle of 38 degrees or below, and 26 for a lower anterior face height of less then 73 mm. The outcome of treatment in the lateral sleep position was unrelated to any mandibular morphology variable. Patients with supine-dependent sleep apnoea defined by a supine apnoea-hypopnoea index of 10 or above and a lateral apnoea-hypopnoea index of below 10 had an odds ratio of 7 to have an orthognathic mandible with an SNB angle of 78 degrees or above. The present study suggests that a successful apnoea reduction using a mandibular advancement device is associated with a normal mandibular plane angle and a small lower anterior face height.
本研究的目的是评估阻塞性睡眠呼吸暂停患者使用口腔内下颌前移装置的治疗效果是否与下颌形态有关。在32名患有阻塞性睡眠呼吸暂停的男性患者中，通过连续多导睡眠图睡眠记录，包括体位，在不使用该装置的一晚和使用该装置的一晚，评估该装置对呼吸暂停和睡眠的影响。在头颅侧位片上测量下颌形态变量。治疗期间仰卧位呼吸暂停低通气指数低于15的比值比，下颌平面角为38度或以下时为17，下颌前下脸高小于73mm时为26。侧卧位睡眠时的治疗效果与任何下颌形态变量均无关。仰卧位呼吸暂停低通气指数为10或以上且侧卧位呼吸暂停低通气指数低于10定义的仰卧位依赖性睡眠呼吸暂停患者，拥有SNB角为78度或以上的正颌下颌的比值比为7。本研究表明，使用下颌前移装置成功减少呼吸暂停与正常的下颌平面角和较小的下颌前下脸高有关。
