从初榨橄榄油中获得的不皂化物部分中某些化合物的细胞生长抑制活性。

Cytostatic activity of some compounds from the unsaponifiable fraction obtained from virgin olive oil.

作者信息

Saenz M T, Garcia M D, Ahumada M C, Ruiz V

机构信息

Laboratori do Farmacognosia, Universidad de Sevilla, 41012 Seville, Spain

出版信息

Farmaco. 1998 Jun 30;53(6):448-9. doi: 10.1016/s0014-827x(98)00043-3.

DOI:10.1016/s0014-827x(98)00043-3

PMID:9786644

Abstract

Oleuropein, tyrosol, squalene and the fraction of sterols and triterpenoid dialcohols from the unsaponifiable fraction obtained from virgin olive oil have been tested for possible cytostatic activity against McCoy cells, using 6-mercaptopurine as a positive control. The samples of sterols and triterpenic dialcohols showed a strong activity.

摘要

已对从初榨橄榄油中获得的不皂化物中的橄榄苦苷、酪醇、角鲨烯以及甾醇和三萜二醇馏分进行了测试，以检测其对 McCoy 细胞的潜在细胞抑制活性，使用 6-巯基嘌呤作为阳性对照。甾醇和三萜二醇样品显示出很强的活性。