Katsman R F, Savenkov P M, Moiseeva E A
Kardiologiia. 1976 Jul;16(7):100-4.
In 77 patients with postinfarction cardiosclerosis the blood serum immunoglobulin level was studied along with some indices of the lipid and protein metabolism. An increased blood level of immunoglobulins A, M and G was observed in postinfarction cardiosclerosis cases, those with hyper-beta-lipoproteinemia, hypercholesterolemia and C-reactive protein having a significantly higher level of immunoglobulin G and than the rest of the patients. In those having an increased content of immunoglobulin G in the blood serum hypo-beta-globulinemia was observed, as well as a considerable increase of the gamma-globulin fraction as compared to those having a normal or decreased level of immunoglobulin G. Proceeding from these data the authors suggest the presence of autoimmune shifts in the patients with postinfarction cardiosclerosis that are closely connected with lipid and protein metabolism disorders.
对77例心肌梗死后心肌硬化患者的血清免疫球蛋白水平以及脂质和蛋白质代谢的一些指标进行了研究。在心肌梗死后心肌硬化病例中观察到免疫球蛋白A、M和G的血液水平升高，那些患有高β脂蛋白血症、高胆固醇血症和C反应蛋白的患者的免疫球蛋白G水平明显高于其他患者。在血清免疫球蛋白G含量增加的患者中，观察到低β球蛋白血症，并且与免疫球蛋白G水平正常或降低的患者相比，γ球蛋白部分显著增加。基于这些数据，作者认为心肌梗死后心肌硬化患者存在自身免疫性变化，这些变化与脂质和蛋白质代谢紊乱密切相关。
