Guinn D A, Kimberlin D F, Wigton T R, Socol M L, Frederiksen M C
Department of Obstetrics and Gynecology, Northwestern University Medical School, General Clinical Research Center-Northwestern Memorial Hospital, Chicago, Illinois 60612, USA.
Am J Perinatol. 1998 Aug;15(8):507-10. doi: 10.1055/s-2007-994075.
The objective of this article is to define normative fetal heart rate (FHR) tracing characteristics between 25-28 weeks' gestation in a low-risk population with normal pregnancy outcomes and to determine which criteria best determine FHR reactivity. Continuous FHR tracings were reviewed from 188 low-risk women participating in a trial of the Mammary Stimulation Test (MST) at 25-28 weeks' gestation. A reactive tracing required the presence of > or =two accelerations in 20 min. Different acceleration criteria were evaluated based upon the width of the acceleration (short vs. long) and the amplitude of the acceleration (10 vs. 15 bpm). Seventy-one percent of the FHR tracings were reactive using the higher amplitude (15 bpm), short criteria. This number increased significantly to 92% when the lower amplitude (10 bpm), short criteria were used (p <0.01). As gestational age advanced, there was a trend toward increased reactivity irrespective of which criteria were used, but these differences were not significant. Reducing the acceleration amplitude criteria to 10 bpm in preterm pregnancies will maximize the number of reactive nonstress tests. This is advantageous because it would improve test specificity and decrease the false-positive rate. Our findings need to be prospectively validated in a high-risk population.
本文的目的是确定妊娠结局正常的低风险人群在妊娠25 - 28周时的正常胎儿心率(FHR)描记特征,并确定哪些标准能最好地判定FHR反应性。回顾了188名在妊娠25 - 28周参与乳腺刺激试验(MST)的低风险女性的连续FHR描记。一份有反应的描记要求在20分钟内出现≥两次加速。根据加速的宽度(短与长)和加速的幅度(10与15次/分钟)评估不同的加速标准。使用较高幅度(15次/分钟)、短标准时,71%的FHR描记有反应。当使用较低幅度(10次/分钟)、短标准时,这一数字显著增加至92%(p<0.01)。随着孕周增加,无论使用哪种标准,反应性都有增加的趋势,但这些差异不显著。在早产妊娠中将加速幅度标准降低至10次/分钟将使有反应的无应激试验数量最大化。这是有利的,因为它将提高试验特异性并降低假阳性率。我们的研究结果需要在高风险人群中进行前瞻性验证。