Mazaev V P, Matveeva Sidel'nikvoa T Ia, Dolbilova V A
Kardiologiia. 1976 Jul;16(7):34-41.
The clinical course and prognosis were studied in 116 patients with clinical signs of ischaemic heart disease when they were hospitalized in an institution in which selective coronary angiography was practiced along with the routine clinical examinations. Control examinations were conducted 2 years later. The dynamics of the clinical manifestations and the results of the disease were evaluated according to the following categories: improvement, stabilization, progressive course, death. All the examined patients were divided into 2 groups: 74 patients with atherosclerotic coronary heart disease proved at angiography, and 72 patients without angiographic signs of coronary pathology. The course of the disease was found to depend on the presence and severity of the atherosclerotic process in the coronary arteries. Essential hypertension aggravated the course and prognosis of the disease. The distinctness of the clinical manifestations of coronary insufficiency, the ischaemic changes in the ECG repolarization complex, the duration of the disease history, and the age of the patients tended to predispose the outcome of the atherosclerotic lesion of the heart. In the group of patients with clinical signs of ischaemic heart disease, but without angiographic changes in the coronaries the result was more favourable, than in those with coronary atherosclerosis. This group, however, included some patients with prognostically unfavourable myocarcial lesions of non-atherosclerotic genesis.
对116例有缺血性心脏病临床症状的患者进行了临床病程及预后研究，这些患者在一家同时开展选择性冠状动脉造影和常规临床检查的机构住院。2年后进行对照检查。根据以下类别评估临床表现的动态变化及疾病结果：改善、稳定、病情进展、死亡。所有受检患者分为两组：74例经血管造影证实患有动脉粥样硬化性冠心病的患者，以及72例无冠状动脉病变血管造影征象的患者。发现疾病的病程取决于冠状动脉粥样硬化进程的存在及严重程度。原发性高血压会加重疾病的病程及预后。冠状动脉供血不足临床表现的明显程度、心电图复极复合体的缺血性改变、病史时长以及患者年龄往往会影响心脏动脉粥样硬化病变的结果。在有缺血性心脏病临床症状但冠状动脉无血管造影改变的患者组中，结果比有冠状动脉粥样硬化的患者组更有利。然而，该组包括一些有非动脉粥样硬化起源的、预后不良的心肌病变患者。
