Abinder A A, Ol'binskaia L I, Kitaeva I T, Beskrovnova N N, Iankin V V
Kardiologiia. 1976 Jul;16(7):88-93.
In 16 rabbit experiments with macrofocal postinfarction cardiosclerosis and 8 control intact animals delayed electron microscopy of myocardium portions from the left ventricle and atria was undertaken, and in 76 clinical observations of patients who had survived a myocardial infarction 1 to 10 years before the examination the indices of the haemodynamic and electrical activity of the atria were compared with those of the contractile function of the left ventricular myocardium under bicycle exercise tests of a growing intensity (with the data of the left ventricular ultrastructure--in the experimental cases). The changes in the left atrium were found to be of an adaptational nature, the right atrium entering the pathogenetic chain when the compensatory capacities of the left atrium got exhausted in the course of the disease, this being a prognostically alerting sign.
对16只患有大面积梗死后期心硬化的兔子和8只对照的健康动物进行了实验，对其左心室和心房部分心肌进行延迟电子显微镜检查；并对76例在检查前1至10年曾患心肌梗死且存活下来的患者进行临床观察，在强度逐渐增加的自行车运动试验中，将心房的血液动力学和电活动指标与左心室心肌收缩功能指标进行比较（在实验病例中，还结合了左心室超微结构的数据）。结果发现，左心房的变化具有适应性，当疾病过程中左心房的代偿能力耗尽时，右心房会进入发病机制链，这是一个预后警示信号。
