Suppr超能文献

胆固醇筛查与治疗模式的决定因素。给决策者的见解。

Determinants of cholesterol screening and treatment patterns. Insights for decision-makers.

作者信息

Davis S K, Ahn D K, Fortmann S P, Farquhar J W

机构信息

Harvard School of Public Health, Division of Public Health Practice, Boston, MA 02115, USA.

出版信息

Am J Prev Med. 1998 Oct;15(3):178-86. doi: 10.1016/s0749-3797(98)00047-6.

Abstract

BACKGROUND

Adult cholesterol screening and treatment policies by the National Cholesterol Education Program recommend that physicians screen all adults aged > 20 [corrected]. On the other hand, the American College of Physicians recommends that healthy young adult men aged > 35 and premenopausal women aged > 45 not be screened due to concerns about the cost of and health risks associated with overuse of pharmacologic therapy in lieu of lifestyle modification.

OBJECTIVES

The objectives of this study were to determine the type of treatment (lifestyle vs. pharmacologic) that physicians actually prescribe for individuals screened for elevated cholesterol.

METHODS

Self-report data were derived from the 1989-1990 cross-sectional survey of the Stanford Five-City Project on 1,883 Latino and Anglo men and women aged 20 to 74 years of age. A four-stage sequential design was conducted using multiple stepwise regression analyses with a significance cutpoint of P < .01.

RESULTS

Young adult men and women were significantly less likely to report ever having been screened (OR 1.02; 95% CI 1.07-1.09). Individuals of low socioeconomic status (SES) were also significantly less likely to report ever being screened (OR, 1.12; CI, 1.08-1.16), as were Latino men and women, regardless of age (OR 1.57; CI, 1.14-2.18). There were no significant differences in the pattern of physician care utilization among low SES or Latino individuals during the previous 12-month period. Among those under physician care to lower cholesterol, young adults were more likely to be prescribed lifestyle modification (OR, 0.95; CI, 0.92-0.98).

CONCLUSIONS

Our results suggest that although young adults are less likely to be screened, if screened they are more likely to be prescribed lifestyle modification than pharmacologic treatment for elevated cholesterol. The lower prevalence of screening among low SES and Latino individuals suggests the need for policy discussions to reduce these disparities.

摘要

背景

国家胆固醇教育计划的成人胆固醇筛查与治疗政策建议医生对所有年龄大于20岁[已修正]的成年人进行筛查。另一方面,美国医师协会建议,由于担心过度使用药物治疗而非生活方式改变带来的成本及健康风险,年龄大于35岁的健康年轻成年男性和年龄大于45岁的绝经前女性不应接受筛查。

目的

本研究的目的是确定医生实际为胆固醇升高接受筛查的个体所开的治疗类型(生活方式治疗还是药物治疗)。

方法

自我报告数据来自斯坦福五城市项目1989 - 1990年对1883名年龄在20至74岁的拉丁裔和盎格鲁男性及女性进行的横断面调查。采用四阶段序贯设计,进行多次逐步回归分析,显著性临界点为P < 0.01。

结果

年轻成年男性和女性报告曾接受筛查的可能性显著更低(比值比1.02;95%置信区间1.07 - 1.09)。社会经济地位(SES)较低的个体报告曾接受筛查的可能性也显著更低(比值比1.12;置信区间1.08 - 1.16),拉丁裔男性和女性也是如此,无论年龄大小(比值比1.57;置信区间1.14 - 2.18)。在过去12个月期间,SES较低或拉丁裔个体在医生诊疗利用模式上没有显著差异。在接受医生治疗以降低胆固醇的人群中,年轻人更有可能被开生活方式改变的处方(比值比0.95;置信区间0.92 - 0.98)。

结论

我们的结果表明,尽管年轻人接受筛查的可能性较小,但如果接受了筛查,对于胆固醇升高,他们比药物治疗更有可能被开生活方式改变的处方。SES较低和拉丁裔个体筛查率较低表明需要进行政策讨论以减少这些差异。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验