Thiébaut R, Birba E, Ouédraogo A, Malvy D
Centre René-Labusquière et Inserm U 330, Université Victor-Ségalen Bordeaux II, France.
Sante. 1998 Jul-Aug;8(4):269-74.
The prevalence of iodine deficiency disorders (IDD) was studied in the health district of Zitenga village (Oubritenga province, Burkina Faso), as part of an assisted development program. The study was designed to assess the prevalence of IDD in a population of more than 2,000 people. A multistage cluster sample of 210 people was randomly selected. The women in the sample were aged 0 to 45 years and the men, 0 to 25 years. Clinical and laboratory results (circulating TSH concentration, T4 and iodine excretion in urine), and dietary intake were recorded. The prevalence of goiter (all grades) was 55.2%. The values recorded for iodine excretion in urine showed that there was moderate iodine deficiency in this area. Blood thyroxine levels were below the laboratory reference range for 63% of the subjects, whereas TSH levels were above the laboratory reference range for 69.3% of the subjects. There was no correlation between hormone status, iodine excretion and goiter. The entire population of this area was deficient in iodine; some individuals had clinical signs of iodine deficiency, such as goiter. Further studies are required to investigate the factors responsible for goiter in this area and iodine supplementation should be provided for the population.
作为一项辅助发展计划的一部分，在布基纳法索乌布里滕加省齐滕加村的健康区对碘缺乏病（IDD）的患病率进行了研究。该研究旨在评估2000多人中碘缺乏病的患病率。随机抽取了一个包含210人的多阶段整群样本。样本中的女性年龄在0至45岁之间，男性年龄在0至25岁之间。记录了临床和实验室结果（循环促甲状腺激素浓度、T4和尿碘排泄量）以及饮食摄入量。甲状腺肿（所有等级）的患病率为55.2%。尿碘排泄量记录值表明该地区存在中度碘缺乏。63%的受试者血液甲状腺素水平低于实验室参考范围，而69.3%的受试者促甲状腺激素水平高于实验室参考范围。激素状态、碘排泄与甲状腺肿之间没有相关性。该地区的整个人口都碘缺乏；一些人有碘缺乏的临床症状，如甲状腺肿。需要进一步研究以调查该地区甲状腺肿的成因，并且应该为该人群提供碘补充剂。
