Fredrickson J M, Rogers J H
Laryngoscope. 1976 Nov;86(11):1738-42. doi: 10.1288/00005537-197611000-00020.
While attempting to devise a valvular device to prevent aspiration in tracheo-esophageal anastomosis, we employed a model in the dog, which we feel would be very useful in the study of other tracheal problems. Essentially, a segment of trachea with its blood supply intact is isolated and turned through 90 degrees. One end of the segment is then anastomosed to the skin whereas the other end is either anastomosed to the gullet or covered with silastic, depending upon the required investigation. In both cases, after an interval of at least nine months, the segment continued to be lined by respiratory epithelium and no stenosis had occurred. Where silastic sheeting was employed to cover the end of the segment, the inner aspect of the silastic was covered with a thin layer of fibrous tissues lined by respiratory epithelium.
在试图设计一种用于防止气管食管吻合术时发生误吸的瓣膜装置的过程中,我们在狗身上采用了一种模型,我们认为该模型在研究其他气管问题时会非常有用。从本质上讲,一段血供完好的气管被分离出来并旋转90度。然后将该段气管的一端与皮肤吻合,而另一端则根据所需的研究情况,要么与食管吻合,要么用硅橡胶覆盖。在这两种情况下,至少经过九个月的间隔后,该段气管仍由呼吸道上皮覆盖,且未发生狭窄。在使用硅橡胶片覆盖该段气管末端的情况下,硅橡胶的内表面覆盖着一层由呼吸道上皮衬里的薄纤维组织。