Bello D, Massie B M
Cardiology Section, San Francisco Department of Veterans Affairs Medical Center, USA.
Cleve Clin J Med. 1998 Oct;65(9):479-89. doi: 10.3949/ccjm.65.9.479.
Amiodarone in low to moderate doses is generally safe in controlling arrhythmias in patients with congestive heart failure (CHF). However, its role is uncertain, because it did not affect the overall mortality rate in three out of four large-scale studies. Whether some subgroups might benefit is a matter of speculation. In patients with sustained ventricular tachycardia, or in those who have survived an episode of sudden death, implantation of a cardioverter-defibrillator may be a better strategy.
低至中等剂量的胺碘酮在控制充血性心力衰竭（CHF）患者的心律失常方面通常是安全的。然而，其作用尚不确定，因为在四项大型研究中有三项研究显示它并未影响总体死亡率。某些亚组患者是否可能从中获益仍有待推测。对于持续性室性心动过速患者或经历过猝死发作后存活下来的患者，植入心脏复律除颤器可能是更好的策略。
