胃肠道毛霉病——一种罕见的孤立性毛霉病。
Gastrointestinal mucormycosis--an uncommon isolated mucormycosis.
作者信息
Sharma M C, Gill S S, Kashyap S, Kataria R, Gupta D K, Sahni P, Acharya S K
机构信息
Department of Pathology, All India Institute of Medical Sciences, New Delhi.
出版信息
Indian J Gastroenterol. 1998 Oct-Dec;17(4):131-3.
BACKGROUND
Isolated mucormycosis of the gastrointestinal tract is uncommon, with only two case reports from India.
OBJECTIVES
To study the clinicopathologic features of gastrointestinal mucormycosis in Indian patients.
METHODS
Eight cases of isolated gastrointestinal mucormycosis, seen over six years (1992-97) are reviewed.
RESULTS
Five of the patients were premature babies or infants, one was a 12-year-old boy, and two were middle aged. Symptomatology included vomiting, bloody diarrhea, upper gastrointestinal bleeding, abdominal lump and abdominal distention. All the neonates presented with intestinal perforation. The duration of symptoms was ten days or less in six cases. Mucormycosis was not suspected clinically in any patient. In six cases the diagnosis was established antemortem from resection or biopsy material. Only two patients received antifungal therapy and only one patient responded.
CONCLUSIONS
Isolated gastrointestinal mucormycosis is not uncommon in India. Early diagnosis may be helpful in reducing the high mortality.
背景
孤立性胃肠道毛霉菌病并不常见，印度仅有两篇病例报告。
目的
研究印度患者胃肠道毛霉菌病的临床病理特征。
方法
回顾了1992年至1997年六年间所见的8例孤立性胃肠道毛霉菌病病例。
结果
5例患者为早产儿或婴儿，1例为12岁男孩，2例为中年患者。症状包括呕吐、血性腹泻、上消化道出血、腹部肿块和腹胀。所有新生儿均出现肠穿孔。6例患者症状持续时间为10天或更短。所有患者临床均未怀疑毛霉菌病。6例患者通过切除或活检材料在生前确诊。仅2例患者接受了抗真菌治疗，仅1例有反应。
结论
孤立性胃肠道毛霉菌病在印度并不少见。早期诊断可能有助于降低高死亡率。
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