Kitsukawa S, Kinn T, Yoshida T, Yonese J, Izutami T, Fukui I, Ishikawa Y
Nihon Hinyokika Gakkai Zasshi. 1998 Sep;89(9):788-91. doi: 10.5980/jpnjurol1989.89.788.
A 44-year-old man suspected of having transitional cell carcinoma (TCC) of the prostate was referred to our hospital. He had a painful semi-erect penis at his first visit. Then needle biopsy of the corpus cavernosum histologically revealed metastatic TCC. CT of the pelvis showed bilateral ureteral obstruction caused by the advanced tumor but no lymph node swelling was found. Under the diagnosis of prostatic TCC with penile metastasis, bilateral percutaneous nephrostomy followed by two courses of combination chemotherapy (IFEP regimen) was carried out, which resulted in the disappearance of priapism. Radical cystectomy with total penectomy was performed. The final pathological diagnosis was corrected to TCC of the urinary bladder with invasion to the prostate and metastasis of the corpus cavernosum and the right obturator lymph node. Enlargement of the prostate proved to be caused by glandular hyperplasia with atypical hyperplasia of the prostate gland. Three courses of adjvent IFEP chemotherapy was given post-operatively and he has been alive with no evidence of the disease for 10 months.
一名疑似患有前列腺移行细胞癌（TCC）的44岁男性被转诊至我院。他初诊时阴茎呈半勃起状态且疼痛。随后阴茎海绵体穿刺活检在组织学上显示为转移性TCC。骨盆CT显示晚期肿瘤导致双侧输尿管梗阻，但未发现淋巴结肿大。在诊断为前列腺TCC伴阴茎转移后，先进行了双侧经皮肾造瘘术，随后进行了两个疗程的联合化疗（IFEP方案），这使得阴茎异常勃起消失。接着实施了根治性膀胱切除术并全阴茎切除术。最终病理诊断修正为膀胱TCC侵犯前列腺，伴有阴茎海绵体和右侧闭孔淋巴结转移。前列腺肿大被证实是由前列腺腺体增生伴非典型增生引起的。术后给予了三个疗程的辅助IFEP化疗，他已存活10个月，无疾病迹象。
