Guillén Toledo J G, Guido Bayardo R G, Vargas Caamano M E
Departamento de alergia e inmunología clínica del Centro Hospitalario, ISSSTE, México.
Rev Alerg Mex. 1998 Jul-Aug;45(4):112-5.
178 439 cases of patients exposed to iodinated contrast media (ICM) corresponding to 137 147 to patients for excretory urography and 41 292 to cholangiography were studied. A direct interrogation making emphasis on personal antecedents of allergy to contrast media, iodinated products usage, nervous system and cardiovascular illnesses was made. Cutaneous test for iodinated contrast media was applied. If the result was positive no study with the ICM was made or it was made with special guidelines. 4302 positives and 1276 false negatives were found. 287 positive cases were premeditated and preventive medication was administered in cases of urticaria asthma/and angioedema with negative cutaneous test histories. There were no deaths registered.
对178439例接受碘化造影剂(ICM)的患者进行了研究,其中137147例用于排泄性尿路造影,41292例用于胆管造影。进行了直接询问,重点关注对造影剂过敏的个人既往史、碘产品使用情况、神经系统和心血管疾病。进行了碘化造影剂的皮肤试验。如果结果为阳性,则不使用ICM进行研究,或者按照特殊指南进行研究。发现4302例阳性和1276例假阴性。287例阳性病例进行了预先处理,对于皮肤试验阴性但有荨麻疹、哮喘和血管性水肿病史的患者给予了预防性用药。没有登记到死亡病例。