Cellular and molecular regulation of eosinophil trafficking to the lung.
作者信息
Hogan S P, Mould A W, Young J M, Rothenberg M E, Ramsay A J, Matthaei K, Young I G, Foster P S
机构信息
Division of Biochemistry, John Curtin School of Medical Research, Australian National University, Acton, Australian Capital Territory.
出版信息
Immunol Cell Biol. 1998 Oct;76(5):454-60. doi: 10.1046/j.1440-1711.1998.00766.x.
Abstract
Airway inflammation is central to the pathogenesis of allergic asthma, and molecules that mediate this process obviously represent targets for therapy. In the present article, we discuss our experiments, which point to CD4+ T cells and IL-5-driven eosinophilia as potential targets for the relief of bronchial hyperreactivity in late-phase asthma.
摘要
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