与复方新诺明治疗相关的肾功能恶化。

Deterioration in renal function in association with co-trimoxazole therapy.

作者信息

Bailey R R, Little P J

出版信息

Med J Aust. 1976 Jun 12;1(24):914, 916. doi: 10.5694/j.1326-5377.1976.tb141169.x.

DOI:10.5694/j.1326-5377.1976.tb141169.x

Abstract

Deterioration in renal function has been observed in four patients who were taking co-trimoxazole. Three patients had stable chronic renal failure, and in two of these there was a further permanent impairment of renal function. The remaining patient received co-trimoxazole while recovering from a short episode of acute oliguric renal failure. It is suggested that co-trimoxazole be withheld, or used with caution in patients with impaired renal function.

摘要

在四名服用复方新诺明的患者中观察到肾功能恶化。三名患者患有稳定的慢性肾衰竭，其中两名患者肾功能进一步出现永久性损害。其余一名患者在从短暂的急性少尿性肾衰竭发作中恢复期间服用了复方新诺明。建议肾功能受损的患者停用复方新诺明，或谨慎使用。