Wechsberg W M, Desmond D, Inciardi J A, Leukefeld C G, Cottler L B, Hoffman J
Substance Abuse Treatment Research Program, Health and Social Policy Division, Research Triangle Institute, Research Triangle Park, North Carolina 27709-2194, USA.
J Psychoactive Drugs. 1998 Jul-Sep;30(3):291-8. doi: 10.1080/02791072.1998.10399704.
Applied research in HIV prevention with out-of-treatment substance abusers takes place in a constantly changing environment. Researchers must be able to identify changes in drug use and sexual risk patterns, develop and evaluate appropriate interventions to respond to those changes, and find ways to make effective use of new technologies as they are developed. An example of this process is the collaborative revision made to NIDA's Standard Intervention for HIV prevention by the final six study sites funded under the NIDA Cooperative Agreements for AIDS Community-Based Outreach and Intervention Research. To illustrate the process of responding to changes in the substance abuse environment, to advances in knowledge about risk, and to newer technologies, this article provides an overview of the history of two federally funded HIV-prevention programs for out-of-treatment substance abusers and reviews recent changes made to the Standard Intervention protocol. The rationale for the changes is discussed, and the substance abuse population in the study is described.
针对未接受治疗的药物滥用者开展的艾滋病病毒预防应用研究是在一个不断变化的环境中进行的。研究人员必须能够识别药物使用和性风险模式的变化，制定并评估应对这些变化的适当干预措施，并找到有效利用新技术的方法。这一过程的一个例子是由美国国立药物滥用研究所（NIDA）艾滋病社区外展和干预研究合作协议资助的最后六个研究地点对NIDA的艾滋病病毒预防标准干预措施进行的协作修订。为了说明应对药物滥用环境变化、风险知识进展和新技术的过程，本文概述了两个由联邦资助的针对未接受治疗的药物滥用者的艾滋病病毒预防项目的历史，并回顾了对标准干预方案最近所做的更改。讨论了更改的理由，并描述了研究中的药物滥用人群。
