Westvik J, Lachman R S
Section of Paediatric Radiology, Department of Radiology, Rikshospitalet, University of Oslo, N-0027 Oslo, Norway.
Pediatr Radiol. 1998 Oct;28(10):764-70. doi: 10.1007/s002470050462.
Objective. To assess the role of coronal and sagittal vertebral clefts in diagnosing skeletal dysplasias. Material and Methods. A search in the database at the International Skeletal Dysplasia Registry revealed 40 different diagnoses in which coronal or sagittal clefts were present, the major groups being: atelosteogenesis, chondrodysplasia punctata, dyssegmental dysplasia, Kniest dysplasia and short rib polydactyly syndrome. We reviewed all firm cases with both AP and lateral films of the spine in these major groups (n = 143), with patients' ages ranging from 20 weeks of gestation up to 26 years of age. Results. Ninety-four percent of all clefts were found in children less than 1 year of age, mainly located in the thoracolumbar region. Fifty-six percent of the clefts were observed in boys. Coronal clefts were more common than sagittal clefts. Clefts were most frequently observed in atelosteogenesis (88%), followed by chondrodysplasia punctata (79%), dyssegmental dysplasia (73%), Kniest dysplasia (63%) and short rib polydactyly syndrome (53%). Conclusion. Vertebral clefts are of major diagnostic value in the groups mentioned above, especially before 1 year of age. The search did not come up with new entities in which vertebral clefts are of major diagnostic value.
目的。评估冠状和矢状位椎体裂在骨骼发育异常诊断中的作用。材料与方法。在国际骨骼发育异常登记处的数据库中进行检索，发现40种不同诊断中存在冠状或矢状位裂隙，主要类别包括：骨发育不全、点状软骨发育不良、节段性发育不良、克尼斯发育不良和短肋多指综合征。我们回顾了这些主要类别中所有有脊柱前后位和侧位X线片的确诊病例（n = 143），患者年龄从妊娠20周直至26岁。结果。所有裂隙中有94%见于1岁以下儿童，主要位于胸腰段。56%的裂隙见于男孩。冠状位裂隙比矢状位裂隙更常见。裂隙最常见于骨发育不全（88%），其次是点状软骨发育不良（79%）、节段性发育不良（73%）、克尼斯发育不良（63%）和短肋多指综合征（53%）。结论。椎体裂在上述类别中具有重要诊断价值，尤其是在1岁之前。该检索未发现椎体裂具有重要诊断价值的新病种。
