de Oliveira-Filho A G, Neto L S, Epelman S
Department of Surgery, Boldrini Children's Cancer Center, Campinas, São Paulo, Brazil.
Pediatr Surg Int. 1998 Oct;13(8):560-3. doi: 10.1007/s003830050403.
Childhood cancer often results in pulmonary metastases, and proper identification and prompt treatment of these lesions increases the survival of these patients. Between 21 May 1995 and 26 June 1996, nine children (five with osteosarcoma, two with Wilms' tumor, and one each with hepatoblastoma and an adrenocortical tumor) underwent median sternotomy at our institution for resection of bilateral pulmonary metastases. These five boys and four girls ranged in age from 2 to 16 years (median, 11 years). Identification and resection of metastases in all lobes of the lungs was greatly facilitated by the median sternotomy approach because both thoracic cavities were fully accessible. In each of five patients, as many as 23 metastases were removed using wedge resection or a stapling device. Multiple biopsies only were obtained from the four remaining patients, whose lesions were too numerous and diffuse for effective resection. All nine patients recovered uneventfully; the median hospitalization was 3 days (range, 2-5 days). We find that median sternotomy is a safe, effective, and relatively simple procedure for resecting bilateral pulmonary metastases in children with cancer.
儿童癌症常导致肺转移,对这些病灶进行正确识别并及时治疗可提高这些患儿的生存率。1995年5月21日至1996年6月26日期间,9名儿童(5例骨肉瘤、2例肾母细胞瘤、1例肝母细胞瘤和1例肾上腺皮质肿瘤)在我院接受了正中开胸手术以切除双侧肺转移瘤。这5名男孩和4名女孩年龄在2至16岁之间(中位数为11岁)。正中开胸手术方法极大地方便了对肺各叶转移瘤的识别和切除,因为两个胸腔都能完全暴露。5例患者中,每例使用楔形切除术或吻合器切除多达23个转移瘤。其余4例患者因病灶太多太弥漫无法有效切除,仅进行了多次活检。所有9例患者均顺利康复;中位住院时间为3天(范围为2至5天)。我们发现,正中开胸手术是切除患癌儿童双侧肺转移瘤的一种安全、有效且相对简单的手术。