Signal transduction: fast lane to transcriptional activation.
作者信息
Rhodes D, Schwabe J W
机构信息
MRC Laboratory of Molecular Biology Hills Road, Cambridge, CB2 2QH, UK.
出版信息
Curr Biol. 1998 Oct 22;8(21):R765-7. doi: 10.1016/s0960-9822(07)00481-2.
PMID:9799727
Abstract
Two newly reported structures of homodimeric 'STAT' transcription factors bound to DNA reveal at atomic resolution the elegant mechanism through which kinase activity at the cell membrane can be transduced into transcriptional activation within the cell nucleus.
摘要
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