急性心肌梗死溶栓失败后的“挽救”治疗
'Rescue' after failed thrombolysis for acute myocardial infarction.
作者信息
Mahy I R, Jennings K P
机构信息
Department of Cardiology, Aberdeen Royal Infirmary, Foresterhill, UK.
出版信息
Postgrad Med J. 1998 Jun;74(872):355-7. doi: 10.1136/pgmj.74.872.355.
Abstract
Prompt restoration of coronary artery patency in acute myocardial infarction is associated with substantial improvements in morbidity and mortality. The pivotal role of thrombolysis and aspirin in achieving these goals is well established. However, despite the success of thrombolytic therapy in large trials, clinical assessment in individual patients often suggests that reperfusion has not occurred after initial therapy. This review considers the validity of such bedside predictions and discusses whether such patients should be managed differently.
摘要
促使急性心肌梗死患者的冠状动脉迅速恢复通畅与发病率和死亡率的显著改善相关。溶栓治疗和阿司匹林在实现这些目标方面的关键作用已得到充分证实。然而，尽管溶栓疗法在大型试验中取得了成功，但对个体患者的临床评估常常显示，初始治疗后并未实现再灌注。本综述探讨了此类床旁预测的有效性，并讨论了对此类患者是否应采取不同的管理方式。
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