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全肺切除术:手术死亡率及生存率分析

Completion pneumonectomy: analysis of operative mortality and survival.

作者信息

Muysoms F E, de la Rivière A B, Defauw J J, Dossche K M, Knaepen P J, van Swieten H A, van den Bosch J M

机构信息

Department of Cardiothoracic Surgery, St Antonius Hospital, Nieuwegein, The Netherlands.

出版信息

Ann Thorac Surg. 1998 Oct;66(4):1165-9. doi: 10.1016/s0003-4975(98)00599-2.

Abstract

BACKGROUND

A single-institution experience with completion pneumonectomy was analyzed to assess operative mortality and late outcome.

METHODS

A consecutive series of 138 completion pneumonectomies from 1975 to 1995 was reviewed, and compared with single-stage pneumonectomies performed during the same period.

RESULTS

Hospital mortality was 13.8%, including 4 intraoperative and 15 postoperative deaths. Hospital mortality was the same for lung cancer (13.2%) as for benign disease (15.5%). It was 37.5% if an early complication of the primary operation was the indication (p = 0.01). If infection of the pleural space was the indication for completion pneumonectomy, hospital mortality was 23.3% (p > 0.05). In 760 single-stage pneumonectomies hospital mortality was 8.7% (p > 0.05). Five-year actuarial survival after completion pneumonectomy was 42.5% for all patients, 32.3% for those with lung cancer, and 58.8% for those with benign disease.

CONCLUSIONS

Hospital mortality for completion pneumonectomy was the same for malignant as for benign indications. It was significantly higher if completion pneumonectomy was done for an early complication of the primary operation. Results at long term of lung cancer patients were the same for single-stage pneumonectomy and completion pneumonectomy.

摘要

背景

分析一家机构完成肺切除术的经验,以评估手术死亡率和远期预后。

方法

回顾了1975年至1995年间连续的138例完成肺切除术病例,并与同期进行的一期肺切除术进行比较。

结果

医院死亡率为13.8%,包括4例术中死亡和15例术后死亡。肺癌患者(13.2%)和良性疾病患者(15.5%)的医院死亡率相同。如果以初次手术的早期并发症为手术指征,死亡率为37.5%(p = 0.01)。如果以胸腔感染作为完成肺切除术的指征,医院死亡率为23.3%(p > 0.05)。在760例一期肺切除术中,医院死亡率为8.7%(p > 0.05)。所有患者完成肺切除术后的5年精算生存率为42.5%,肺癌患者为32.3%,良性疾病患者为58.8%。

结论

完成肺切除术的医院死亡率在恶性和良性指征方面相同。如果因初次手术的早期并发症而进行完成肺切除术,死亡率显著更高。肺癌患者一期肺切除术和完成肺切除术的长期结果相同。

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