Lau K O, Li M K, Foo K T
Department of Urology, Singapore General Hospital, Singapore.
Urology. 1998 Nov;52(5):829-33. doi: 10.1016/s0090-4295(98)00285-4.
To evaluate the long-term results of transurethral microwave thermotherapy (TUMT) for benign prostatic hyperplasia (BPH) with up to 5 years of follow-up at our institution.
From October 1991 to November 1993, 106 patients were treated for BPH with TUMT using the Prostatron 2.0. Of the 106 patients, 64 were available for evaluation of symptoms (Madsen-Iverson score), uroflow, residual urine, and retreatment rate at a mean follow-up of 50+/-5.4 months (mean+/-SD).
The mean age of the patients was 65.2+/-9.8 years. Thirty-two patients (50.0%) were treated with one session of TUMT. Additional treatments were required for 32 patients (50.0%). Three patients had two sessions of TUMT, 14 underwent transurethral resection of prostate, and 3 had laser prostatectomy. Twelve patients received medical therapy. The mean symptom score decreased significantly from 12.9+/-2.5 to 5.7+/-3.6 (P = 0.001). The mean peak flow rates and postvoid residual volume showed little difference before and after TUMT. On the basis of the criteria described by Poincelet and Cathaud the overall clinical efficacy rate was 39.1% (15.6% complete response and 23.5% partial response). No obvious clinical parameter was useful to predict favorable outcome after TUMT.
The present study showed that the efficacy rate of TUMT with the Prostatron 2.0 at 50 months was 39.1 %. None of the preoperative clinical factors was predictive of a favorable outcome.
评估经尿道微波热疗(TUMT)治疗良性前列腺增生(BPH)的长期效果,在我们机构进行长达5年的随访。
1991年10月至1993年11月,106例BPH患者使用Prostatron 2.0进行TUMT治疗。106例患者中,64例可用于评估症状(Madsen - Iverson评分)、尿流率、残余尿量和再治疗率,平均随访时间为50±5.4个月(平均±标准差)。
患者的平均年龄为65.2±9.8岁。32例患者(50.0%)接受了一次TUMT治疗。32例患者(50.0%)需要额外治疗。3例患者进行了两次TUMT治疗,14例接受了经尿道前列腺切除术,3例进行了激光前列腺切除术。12例患者接受了药物治疗。平均症状评分从12.9±2.5显著降至5.7±3.6(P = 0.001)。TUMT前后平均最大尿流率和排尿后残余尿量差异不大。根据Poincelet和Cathaud描述的标准,总体临床有效率为39.1%(完全缓解15.6%,部分缓解23.5%)。没有明显的临床参数可用于预测TUMT后的良好结果。
本研究表明,使用Prostatron 2.0进行TUMT在50个月时的有效率为39.1%。术前临床因素均不能预测良好结果。