Kay J H, Zubiate P, Mendez M A, Vanstrom N, Yokoyama T
Am Heart J. 1978 Aug;96(2):253-62. doi: 10.1016/0002-8703(78)90094-7.
There has been skepticism since the early days of open heart surgery that good long-term or even short-term results were possible with repair of pure mitral insufficiency. The authors report 145 patients in whom a markedly insufficient mitral valve was repaired 6 months to 17 years previously and another 55 patients in whom repair of the insufficient mitral valve was performed along with myocardial revascularization from 6 months to 7 years previously. Comparative data with other published work reveals superior results with repair than with replacement with Starr-Edwards and Hancock glutaraldehyde-treated porcine valves and with far less emboli. Conservatism is urged in operating upon patients with mitral insufficiency. Repair of the valve rather than replacement is stressed for those patients requiring surgery.
自心脏直视手术早期以来,对于单纯二尖瓣关闭不全修复能否取得良好的长期甚至短期效果一直存在怀疑态度。作者报告了145例患者,他们在6个月至17年前接受了明显关闭不全的二尖瓣修复手术,另有55例患者在6个月至7年前在进行心肌血运重建的同时接受了关闭不全二尖瓣的修复手术。与其他已发表研究的对比数据显示,修复手术的效果优于使用斯塔尔-爱德华兹瓣膜和汉考克戊二醛处理猪瓣膜进行置换手术,且栓塞情况要少得多。对于二尖瓣关闭不全患者的手术治疗,强烈建议采取保守态度。对于那些需要手术的患者,强调瓣膜修复而非置换。