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经皮腔内颈动脉血管成形术后的再狭窄与重塑

[Restenosis and remodeling after percutaneous transluminal carotid angioplasty].

作者信息

Madrid A, Gil-Peralta A, González-Marcos J R, Otero A, Crespo P

机构信息

Neurólogo, Servicio de Neurología del Hospital Universitario Virgen del Rocío, Sevilla, España.

出版信息

Rev Neurol. 1998 Oct;27(158):649-52.

PMID:9803516
Abstract

INTRODUCTION

The characteristics of restenosis and remodeling after carotid percutaneous transluminal angioplasty (PTA) were badly known.

OBJECTIVE

To describe these characteristics in our series of carotid PTA.

PATIENTS AND METHODS

A total of 78 cases of PTA for symptomatic > 70% atherosclerotic stenosis of the extracranial internal carotid artery, were selected from our series of PTA if follow-up was > 12 months. All of them were followed with extracranial continuous-wave Doppler.

RESULTS

Restenosis of any degree was found in 17 cases (21.79%) and always asymptomatic. A restenosis > or = 70% was found in 5 cases (6.4%). Restenosis was mainly found in cases without residual stenosis nor dissection after PTA (p = 0.002). Restenosis was found in 16 cases (94.11%) in the first 6-months, with no progression thereafter. Remodeling of residual stenosis was frequent (17 cases; 53.11%) and found mainly during the first month after PTA. Its incidence was highest in patients with dissection treated with heparin. In cases with restenosis, remodeling was infrequent, incomplete and occurred after 18-24 months.

CONCLUSIONS

  1. Significant restenosis after PTA due to myointimal proliferation, was infrequent. All cases were asymptomatic, under antiplatelet treatment. A new interventional procedure might not be necessary. 2. Complete remodeling was frequently found after 1-month control, mainly in arteries with some residual stenosis and dissection after PTA.
摘要

引言

颈动脉经皮腔内血管成形术(PTA)后再狭窄和重塑的特征鲜为人知。

目的

描述我们系列颈动脉PTA的这些特征。

患者和方法

从我们的PTA系列中选取78例有症状的颅外颈内动脉粥样硬化狭窄>70%且接受PTA治疗的患者,若随访时间>12个月。所有患者均采用颅外连续波多普勒进行随访。

结果

17例(21.79%)发现有任何程度的再狭窄,且均无症状。5例(6.4%)发现再狭窄≥70%。再狭窄主要见于PTA后无残余狭窄及夹层的病例(p = 0.002)。16例(94.11%)在最初6个月内发现再狭窄,此后无进展。残余狭窄的重塑很常见(17例;53.11%),主要在PTA后第一个月发现。其发生率在接受肝素治疗的夹层患者中最高。在有再狭窄的病例中,重塑不常见、不完全且发生在18 - 24个月后。

结论

  1. 因肌内膜增生导致的PTA后显著再狭窄并不常见。所有病例均无症状,接受抗血小板治疗。可能无需新的介入治疗。2. 在1个月复查后常发现完全重塑,主要见于PTA后有一些残余狭窄和夹层的动脉。

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