Pickles A
MRC Child Psychiatry Unit, Institute of Psychiatry, London, UK.
Stat Methods Med Res. 1998 Sep;7(3):235-51. doi: 10.1177/096228029800700303.
Statisticians working in psychiatric epidemiology regularly confront a variety of problems that are rare in other branches of epidemiology. These problems range from the frequent absence of 'objective' biological markers and consequent reliance on informant and self-reports of considerable fallability, to the perhaps corresponding frequent use of multivariate statistical methods such as latent variable modelling. Equally, such difficulties can be regarded as challenges that offer the statistician a critical role.
从事精神疾病流行病学研究的统计学家经常面临各种在其他流行病学分支中很少见的问题。这些问题包括经常缺乏“客观”的生物学标志物,因此不得不依赖可靠性存疑的信息提供者报告和自我报告,到可能相应地频繁使用多元统计方法,如潜在变量建模。同样,这些困难也可以被视为挑战,赋予了统计学家至关重要的角色。