Guzmán M G, Rodríguez R, Resik S, Alvarez M, Morier L, Castillo A, Kourí G, Maś P
Instituto de Medicina Tropical Pedro Kourí.
Rev Cubana Med Trop. 1995;47(1):32-5.
This paper reports on the physical and chemical characteristics of agents isolated from serum samples of patients presenting with epidemic neuropathy. The behaviour of isolated enteroviruses was as described for such viruses. Mild cytopathogenic effects-producing agents behaved in a variable form regarding sensitivity to chloroform; on the other hand they were neither sensitive to phosphonoacetic acid (PAA) nor to guanidine hydrochloride (GHC1) and grew in cells previously treated with bromodeoxyuridine (BDUR). These results suggest the presence of agents resembling enteroviruses and enveloped viruses. Further studies for the characterization of such agents need to be performed.
本文报道了从流行性神经病患者血清样本中分离出的病原体的物理和化学特性。分离出的肠道病毒的行为与这类病毒的描述一致。产生轻度细胞病变效应的病原体对氯仿的敏感性表现出不同形式;另一方面,它们既对膦甲酸(PAA)不敏感,也对盐酸胍(GHC1)不敏感,并且能在先前用溴脱氧尿苷(BDUR)处理过的细胞中生长。这些结果表明存在类似肠道病毒和包膜病毒的病原体。需要对这类病原体进行进一步的特性研究。