Bezon E, Karaterki A, Barra J A
Service de chirurgie cardiaque, thoracique et vasculaire, CHU, La Cavale Blanche, Brest.
Arch Mal Coeur Vaiss. 1998 Sep;91(9):1139-44.
The aim of this study was to precise the circumstances of the failure of coronary artery bypass graft by internal thoracic artery (ITA).
It was a retrospective study which compared angiographic results between several techniques of ITA graft; 512 coronary artery bypass graft have been realized on 302 patients: 115 single left ITA grafts, 78 sequential left ITA grafts, 48 bilateral pedicled ITA grafts, 61 bilateral ITA Y grafts. The mean interval between operation and reangiography was 17.3 months (s = 4.1 months). Graft failures were occluded and non functioning ITA grafts (threadlike ITA).
There were 11 occluded grafts (2%) and 19 non functionning grafts (4%). There was no difference of failure rate between the 4 techniques of ITA grafts (p > 0.05). The failure rate for right ITA grafts 13% was higher than for the left ITA grafts 4% (p < 0.001). The failure rate for obtuse marginal branch grafts 13% was higher than for left anterior descending artery grafts 3% (p < 0.001).
The extended use of ITA doesn't increase the risk of graft failure rate. The patency of obtuse marginal branch ITA graft is less than the patency of left anterior descending artery or diagonal branch ITA grafts.
本研究旨在明确胸廓内动脉(ITA)冠状动脉旁路移植失败的情况。
这是一项回顾性研究,比较了几种ITA移植技术的血管造影结果;对302例患者实施了512例冠状动脉旁路移植术:115例单左ITA移植、78例序贯左ITA移植、48例双侧带蒂ITA移植、61例双侧ITA Y形移植。手术与再次血管造影之间的平均间隔时间为17.3个月(标准差=4.1个月)。移植失败是指ITA移植血管闭塞和无功能(条索状ITA)。
有11例移植血管闭塞(2%)和19例无功能移植血管(4%)。4种ITA移植技术之间的失败率无差异(p>0.05)。右ITA移植的失败率为13%,高于左ITA移植的4%(p<0.001)。钝缘支移植的失败率为13%,高于左前降支移植的3%(p<0.001)。
ITA的广泛应用不会增加移植失败率的风险。钝缘支ITA移植的通畅率低于左前降支或对角支ITA移植的通畅率。