Chaffee N R
Department of Prosthodontics, University of North Carolina School of Dentistry, Chapel Hill, USA.
J Prosthodont. 1998 Sep;7(3):155-60. doi: 10.1111/j.1532-849x.1998.tb00198.x.
Scleroderma is a multisystem connective tissue disease of unknown etiology, which is characterized by inflammation, vascular, and fibrotic changes of the skin as well as various internal organs. This article will review the systemic form of scleroderma known as CREST syndrome, its clinical manifestations including the dentofacial complications, as well as provide information to assist the prosthodontist in managing the dental treatment for patients with this disease.
硬皮病是一种病因不明的多系统结缔组织疾病，其特征为皮肤以及各种内脏器官出现炎症、血管和纤维化改变。本文将综述被称为CREST综合征的系统性硬皮病形式、其临床表现（包括牙颌面并发症），并提供信息以协助口腔修复医生对患有该疾病的患者进行牙科治疗。
